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Irsogladine
$50 – $55
Web ID
– HY-B0327
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C9H7Cl2N5
References
– [1]Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31.|[2]Kawasaki, Y., et al., Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway. Pancreas, 2002. 25(4): p. 373-7.|[3]Kyoi, T., et al., Phosphodiesterase inhibition by a gastroprotective agent irsogladine: preferential blockade of cAMP hydrolysis. Life Sci, 2004. 75(15): p. 1833-42.
CAS Number
– 57381-26-7
Molecular Weight
– 256.09
Compound Purity
– 99.97
SMILES
– NC1=NC(N)=NC(C2=CC(Cl)=CC=C2Cl)=N1
Clinical Information
– Launched
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 120 mg/mL (ultrasonic)|H2O : 1.2 mg/mL (ultrasonic)
Target
– mAChR;Phosphodiesterase (PDE)
Isoform
– PDE4
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
