Irsogladine

$50$55

Web ID

– HY-B0327

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C9H7Cl2N5

References

– [1]Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31.|[2]Kawasaki, Y., et al., Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway. Pancreas, 2002. 25(4): p. 373-7.|[3]Kyoi, T., et al., Phosphodiesterase inhibition by a gastroprotective agent irsogladine: preferential blockade of cAMP hydrolysis. Life Sci, 2004. 75(15): p. 1833-42.

CAS Number

– 57381-26-7

Molecular Weight

– 256.09

Compound Purity

– 99.97

SMILES

– NC1=NC(N)=NC(C2=CC(Cl)=CC=C2Cl)=N1

Clinical Information

– Launched

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 120 mg/mL (ultrasonic)|H2O : 1.2 mg/mL (ultrasonic)

Target

– mAChR;Phosphodiesterase (PDE)

Isoform

– PDE4

Pathway

– GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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