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Products Details
Product Description
– IRE1α kinase-IN-4 (compound 6) is a potent IRE1α inhibitor with an Ki of 140 nM. IRE1α kinase-IN-4 is the ATP-competitive ligands of IRE1α[1].
Web ID
– HY-145419
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H31N7O2
References
– [1]Feldman HC, et al. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 Nov;17(11):1148-1156.
CAS Number
– 2771006-45-0
Molecular Weight
– 509.60
SMILES
– O=C(NC1CC1)NC(C2=C3C=CC=C2)=CC=C3OC4=NC=CC=C4C5=NC(N[C@H]6CC[C@H](N)CC6)=NC=C5
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– IRE1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
