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Products Details
Product Description
– IRE1α kinase-IN-9 (compound 2) is a potent IRE-1α inhibitor，exhibits an average IC50 value of <0.1 μM. IRE1α kinase-IN-9 can be used for research in diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD)[1].
Web ID
– HY-153475
Shipping
– Room temperature
Molecular Formula
– C24H24N2O6
References
– [1]Zeng Q, et al. Benzoheterocyclecarboxaldehyde derivatives as IRE-1α inhibitors and their preparation and use for the treatment of diseases. World Intellectual Property Organization, WO2011127070 A2. 2011-10-13.
CAS Number
– 1338933-30-4
Molecular Weight
– 436.46
SMILES
– O=CC1=C(OC(C(C2=CC=C(C(NCCN3CCOCC3)=O)C=C2)=C4C)=O)C4=CC=C1O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– IRE1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
