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Products Details
Product Description
– Irampanel (BIIR 561) is an AMPA receptor and voltage-dependent sodium channel blocker. Irampanel inhibits kainate-induced currents in rat cortical neurons[1].
Web ID
– HY-15082
Shipping
– Room temperature
Molecular Formula
– C18H19N3O2
References
– [1]Weiser T, et al. Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):419-26.
CAS Number
– 206260-33-5
Molecular Weight
– 309.36
SMILES
– CN(C)CCOC(C=CC=C1)=C1C2=NC(C3=CC=CC=C3)=NO2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR;Sodium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
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