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Products Details
Product Description
– IRAK4-IN-26 (Compound 21) is a IRAK4 inhibitor (IC50: 6.2 nM). IRAK4-IN-26 displays an oral bioavailability of 21%. IRAK4-IN-26 can be used for research of inflammatory and autoimmune disorders[1].
Web ID
– HY-155519
Shipping
– Room temperature
Molecular Formula
– C22H23N5O3
References
– [1]Hao Y, et al. Synthesis and evaluation of dihydrofuro[2,3-b]pyridine derivatives as potent IRAK4 inhibitors. Eur J Med Chem. 2023 Oct 5;258:115616.
Molecular Weight
– 405.45
SMILES
– O=C(NC1=CC=CC(C2=CN(C)N=C2)=N1)C(C(OC3CC3)=N4)=CC5=C4OC(C)(C)C5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– IRAK
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
