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Products Details
Product Description
– IRAK4-IN-24 (compound 16) is a potent IRAK4 inhibitor, with high clearance (Cl) and poor oral bioavailability. IRAK4-IN-24 can be used for research in inflammatory and autoimmune disorders.
Web ID
– HY-149345
Shipping
– Room temperature
Molecular Formula
– C19H19N5O3
References
– [1]Hao Y, et al. Synthesis and evaluation of dihydrofuro [2, 3-b] pyridine derivatives as potent IRAK4 inhibitors[J]. European Journal of Medicinal Chemistry, 2023: 115616.
Molecular Weight
– 365.39
SMILES
– O=C(NC1=CC=CC(C2=CN(C)N=C2)=N1)C3=CC(CC(C)(C)O4)=C4N=C3O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– IRAK
Isoform
– IRAK4
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
