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Products Details
Product Description
– IRAK4-IN-17 (Compound 5) is a potent IRAK4 inhibitor with the IC50 of 1.3 nM[1]. IRAK4-IN-17 can be used in large B-cell lymphoma (DLBCL) research[1].
Web ID
– HY-150594
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H20F2N8O
References
– [1]Yun Chen, et al. Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma. Eur J Med Chem. 2020 Mar 15;190:112092.
CAS Number
– 2183503-33-3
Molecular Weight
– 390.39
SMILES
– O=C(C1=CN=C2C=CC(N[C@H]3CNCCC3)=NN21)NC4=CN(C)N=C4C(F)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IRAK;NF-κB
Isoform
– IRAK4
Pathway
– Immunology/Inflammation;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
