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Product Description
– IQTub4P is a potent microtubule (MT) inhibitor. IQTub4P has the cytotoxicity in in HeLa cells, with EC50 of 170 nM. IQTub4P inhibits microtubule structure and function. IQTub4P is well-tolerated in vivo[1].
Web ID
– HY-146692
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H18NNa2O8P
References
– [1]Kraus Y, Glas C, Melzer B, et al. Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors. Eur J Med Chem. 2020;186:111865.
CAS Number
– 2376321-67-2
Molecular Weight
– 465.30
SMILES
– O=P(O[Na])(O[Na])OC1=CC2=C(C(C3=CC(OC)=C(C(OC)=C3)OC)=NC=C2)C=C1OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
