Products Details

Product Description

– IQTub4P is a potent microtubule (MT) inhibitor. IQTub4P has the cytotoxicity in in HeLa cells, with EC50 of 170 nM. IQTub4P inhibits microtubule structure and function. IQTub4P is well-tolerated in vivo[1].

Web ID

– HY-146692

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C19H18NNa2O8P

References

– [1]Kraus Y, Glas C, Melzer B, et al. Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors. Eur J Med Chem. 2020;186:111865.

CAS Number

– 2376321-67-2

Molecular Weight

– 465.30

SMILES

– O=P(O[Na])(O[Na])OC1=CC2=C(C(C3=CC(OC)=C(C(OC)=C3)OC)=NC=C2)C=C1OC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Microtubule/Tubulin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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