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Products Details
Product Description
– iPRMT1 is a potent and selective PRMT1 inhibitor for breast cancer research. iPRMT1 inhibits breast cancer cell growth in vitro and in vivo with EC50 values of 90, 70, and 9 nM in MCF7, T47D, and MDA-MB-231 cells, respectively[1].
Web ID
– HY-157151
Shipping
– Room temperature
Molecular Formula
– C24H24N6O2
References
– [1]Li WJ, et al. Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis. Cell Rep. 2023 Nov 7;42(11):113385.
Molecular Weight
– 428.49
SMILES
– OC(CC1)CCN1C(C=C2)=CC=C2NC3=NC(N4[C@H]5CC6=CC=CC=C46)=C(C=N3)NC5=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
