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Ipivivint
$780 – $6,500
Products Details
Product Description
– Ipivivint (compound 38) is a potent CDC-like kinase (CLK) inhibitor with EC50s of 1 nM, 7 nM for CLK2 and CLK3, respectively. Ipivivint inhibits Wnt pathway (EC50=13 nM)[1].
Web ID
– HY-137443
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H21FN8
References
– [1]Betty Tam, et al. Methods of treating cancer using a clk inhibitor. WO2020006115A1.
CAS Number
– 1481617-15-5
Molecular Weight
– 464.50
Compound Purity
– 99.65
SMILES
– CN(C)CC1=CC(C2=CN=C(NN=C3C(N4)=NC5=C4C(C6=CC(F)=CC=C6)=CN=C5)C3=C2)=CN=C1
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– CDK;Wnt
Isoform
– CDK2;CDK3
Pathway
– Cell Cycle/DNA Damage;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
