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Products Details
Product Description
– Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Web ID
– HY-I0096S
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C8 13CH7NO2
References
– [1]2-Indolecarboxylic acid.|[2]J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1216839-31-4
Molecular Weight
– 162.15
SMILES
– O=[13C](O)C1=CC2=CC=CC=C2N1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;iGluR;Isotope-Labeled Compounds
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
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