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Indole-2-carboxylic acid
SKU
HY-I0096-10mM/1mL
Category Natural Products
Tags Endogenous Metabolite;iGluR, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling, Neurological Disease
$50 – $55
Products Details
Product Description
– Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Web ID
– HY-I0096
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C9H7NO2
References
– [1]2-Indolecarboxylic acid.|[2]J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3.
CAS Number
– 1477-50-5
Molecular Weight
– 161.16
Compound Purity
– 99.97
SMILES
– O=C(C(N1)=CC2=C1C=CC=C2)O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic)
Target
– Endogenous Metabolite;iGluR
Isoform
– Human Endogenous Metabolite;NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.