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Indimitecan
$350 – $2,850
Products Details
Product Description
– Indimitecan (LMP776) is a topoisomerase I (Top1) inhibitor with anticancer activities[1].
Web ID
– HY-18350
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H21N3O6
References
– [1]Cinelli MA, et al. Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons. J Med Chem. 2012 Dec 27;55(24):10844-62.
CAS Number
– 915360-05-3
Molecular Weight
– 459.45
Compound Purity
– 98.03
SMILES
– O=C1C2=CC(OC)=C(OC)C=C2C3=C(C(C=C(OCO4)C4=C5)=C5C3=O)N1CCCN6C=NC=C6
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 8.33 mg/mL (ultrasonic;warming;adjust pH to 3 with HCl;heat to 60°C)
Target
– Topoisomerase
Isoform
– Topo I
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
