Indatraline (hydrochloride)

$264$422

Products Details

Product Description

– Indatraline hydrochloride (Lu 19-005) is a non-selective monoamine transporter inhibitor that blocks the reuptake of neurotransmitters (dopamine, serotonin, and norepinephrine). Indatraline hydrochloride can be used for the research of antidepressive. Indatraline hydrochloride induces autophagy while simultaneously inhibiting cell proliferation. Indatraline hydrochloride may also serve to direct the development of new agents for autophagy-related diseases such as atherosclerosis or restenosis[1].

Web ID

– HY-110019

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C16H16Cl3N

References

– [1]Cho YS, et al. Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway. Sci Rep. 2016; 6:34655.

CAS Number

– 96850-13-4

Molecular Weight

– 328.66

SMILES

– CN[C@@H]1C[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Dopamine Transporter;Serotonin Transporter

Pathway

– Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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