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Products Details
Product Description
– IMM-01 is a formin agonist that inhibits DID-DAD (diaphanous inhibitory domain-diaphanous autoregulatory domain) binding with an IC50 140 nM. IMM-01 acts by disrupting the autoinhibitory bond between the DID and DAD domain and thus activates formins. IMM-01 shows anticancer effects[1].
Web ID
– HY-124808
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C12H17N3O2S
References
– [1]L Leanne Lash, et al. Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells. Cancer Res. 2013 Nov 15;73(22):6793-803.
CAS Number
– 218795-74-5
Molecular Weight
– 267.35
SMILES
– OC1=CC=C(/C=N/NC(NC(C)(C)C)=S)C(O)=C1
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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