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Imiquimod-d9
$569
Only 1000 item(s) left in stock.
Products Details
Product Description
– Imiquimod-d9 is deuterium labeled Imiquimod. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19[1][2].
Web ID
– HY-B0180S1
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C14H7D9N4
References
Р[1]Aditya K Gupta, et al. Imiquimod: a review. J Cutan Med Surg. Nov-Dec 2002;6(6):554-60.|[2]Athina Angelopoulou, et al. Imiquimod РA toll like receptor 7 agonist РIs an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858.|[3]Michael P Sch̦n, et al. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol. 2006 Jun;126(6):1338-47.|[4]Yuji Kan, et al. Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol. 2012 Oct;86(19):10338-46.|[5]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 2712126-48-0
Molecular Weight
– 249.36
SMILES
– NC1=NC2=CC=CC=C2C3=C1N=CN3C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Autophagy;HSV;Isotope-Labeled Compounds;SARS-CoV;Toll-like Receptor (TLR)
Pathway
– Anti-infection;Autophagy;Immunology/Inflammation;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
