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Products Details
Product Description
– Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC50 value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].
Web ID
– HY-148264
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C18H9F6NO2
References
– [1]Jiping Fu, et al. Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors. Patent. WO2020214853A1.
CAS Number
– 2511247-29-1
Molecular Weight
– 385.26
SMILES
– O[C@]12C3=C(C(F)(C1(F)F)F)C=CC(OC4=CC(C#N)=CC(F)=C4)=C3[C@H](C2)F
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
