Download Files:
IM-54
$160
Only 1000 item(s) left in stock.
Products Details
Product Description
– IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death[1][2].
Web ID
– HY-108351
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H23N3O2
References
– [1]Kosuke Dodo, et al. Indolylmaleimide Derivative IM-17 Shows Cardioprotective Effects in Ischemia-Reperfusion Injury. ACS Med Chem Lett. 2018 Mar 8; 9(3): 182-187.|[2]Mikiko Sodeoka, et al. Development of selective inhibitors of necrosis. Chem Rec. 2010 Oct;10(5):308-14.
CAS Number
– 861891-50-1
Molecular Weight
– 325.40
Compound Purity
– 99.31
SMILES
– O=C(C(C1=CN(C)C2=C1C=CC=C2)=C3NCCCCC)N(C)C3=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Necroptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
