Download Files:
Illudin S
$320 – $1,020
Products Details
Product Description
– Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells[1][2][3][4].
Web ID
– HY-125098
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C15H20O4
References
– [1]Hansruedi Glatt, et al. Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells. Arch Toxicol . 2014 Jan;88(1):161-9.|[2]Nicolaas G J Jaspers, et al. Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways. DNA Repair (Amst). 2002 Dec 5;1(12):1027-38.|[3]Illudin S, the sole antiviral compound in mature fruiting bodies of Omphalotus illudens|[4]M J Kelner, et al. Preclinical evaluation of illudins as anticancer agents. Cancer Res. 1987 Jun 15;47(12):3186-9.
CAS Number
– 1149-99-1
Molecular Weight
– 264.32
Compound Purity
– 98.01
SMILES
– O=C1C2=C[C@](C)([C@@H](C2=C(C3([C@@]1(C)O)CC3)C)O)CO
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Apoptosis;DNA Alkylator/Crosslinker
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
