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IL-17A inhibitor 1
$750 – $6,100
Products Details
Product Description
– IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1].
Web ID
– HY-139206
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H27F5N8O4
References
– [1]COATES DAVID ANDREW, et al. IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS. Patent WO2020146194.
CAS Number
– 2452464-73-0
Molecular Weight
– 586.51
Compound Purity
– 99.87
SMILES
– O=C(C1=NON=C1C)N[C@@H](C2CCC(F)(CC2)F)C3=CN(N=CC([C@H](N4C[C@H](NC4=O)C(F)(F)F)COC)=C5)C5=N3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Interleukin Related
Isoform
– IL-17
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
