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IL-17A antagonist 1
$120 – $980
Products Details
Product Description
– IL-17A antagonist 1 (compound 1) is an IL-17A antagonist, with a Kd of 0.66 μM and an IC50 of 1.14 μM[1].
Web ID
– HY-101913
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C33H41FN6O4
References
– [1]Liu S, et al. Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep. 2016 Aug 16;6:30859.
CAS Number
– 2205034-18-8
Molecular Weight
– 604.71
Compound Purity
– 99.74
SMILES
– O=C(N(C)C)CC1(CC(NCCC2=CC=C(NC([C@H](CC3=CC=CC=C3F)NC(C4=CC=NN4C)=O)=O)C=C2)=O)CCCC1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Interleukin Related
Isoform
– IL-17
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
