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Products Details
Product Description
– IKK-IN-4 is a potent and selective IkappaB kinase 2 (IKKβ orIKK2) inhibitor, with IC50s of 45 and 650 nM for IKKβ and IKKα, respectively[1].
Web ID
– HY-136393
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H19N5S
References
– [1]Belema M, et al. Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitors. Bioorg Med Chem Lett. 2007;17(15):4284‐4289.
CAS Number
– 615529-94-7
Molecular Weight
– 337.44
SMILES
– CC1=CN=C2C(NC)=NC(C=C(C3=CC=CC(CCN)=C3)S4)=C4N21
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– IKK
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
