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Products Details
Product Description
– IKK-IN-3 is a potent and selective IkappaB kinase 2 (IKK2 or IKKβ) inhibitor, with IC50s of 19 and 400 nM for IKK2 and IKK1 (or IKKα), respectively[1].
Web ID
– HY-136392
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H17N5S
References
– [1]Kempson J , et al. Novel tricyclic inhibitors of IkappaB kinase. J Med Chem. 2009;52(7):1994‐2005.
CAS Number
– 615528-53-5
Molecular Weight
– 323.42
SMILES
– NCCNC1=NC(C=C(C2=CC=CC=C2)S3)=C3N4C1=NC=C4C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– IKK
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
