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iKIX1
$41 – $715
Products Details
Product Description
– iKIX1 is an antifungal agent and resensitizes drug-resistant C. glabrata to azole antifungals in vitro. iKIX1 inhibits the interaction between the KIX domain of the mediator subunit CgGal11A and the activation domain of CgPdr1, the IC50 and Ki values are 190.2 μM and 18 μM, respectively. iKIX1 is used for the study of multidrug resistance and C. glabrata infection[1].
Web ID
– HY-124952
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H8Cl2N4OS
References
– [1]Joy L Nishikawa, et al.Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction. Nature. 2016 Feb 25;530(7591):485-9.
CAS Number
– 656222-54-7
Molecular Weight
– 303.17
Compound Purity
– 99.36
SMILES
– O=C(NNC(NC1=CC=C(Cl)C(Cl)=C1)=S)CC#N
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– Fungal
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
