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Products Details
Product Description
– IIIM-8 is a melanogenesis inhibitor. IIIM-8 inhibits pigment production both in vitro and in vivo without incurring any cytotoxicity in Human Adult Epidermal Melanocytes (HAEM). IIIM-8 can be used for hyperpigmentation disorders research[1].
Web ID
– HY-155189
Shipping
– Room temperature
Molecular Formula
– C14H17NO4
References
– [1]Naikoo SH, et al. Inhibition of melanogenesis by 3-(1′-methyltetrahydropyridinyl)-2,4-6-trihydroxy acetophenone via suppressing the activity of cAMP response element-binding protein (CREB) and nuclear exclusion of CREB-regulated transcription coactivator 1 (CRTC1). Eur J Pharmacol. 2023 Aug 5;952:175734.
CAS Number
– 1128053-62-2
Molecular Weight
– 263.29
SMILES
– OC1=C(C(C)=O)C(O)=C(C2=CCN(C)CC2)C(O)=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Melanocortin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
