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IHR-1
Products Details
Product Description
– IHR-1 is a cell membrane impermeable Smo antagonist[1].
Web ID
– HY-110240
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H12Cl4N2O2
References
– [1]Chih-Wei Fan, et al. The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Chem Biol. 2014 Dec 18;21(12):1680-9.
CAS Number
– 548779-60-8
Molecular Weight
– 454.13
SMILES
– O=C(C1=C(C=CC(Cl)=C1)Cl)NC(C=C2)=CC=C2NC(C3=C(C=CC(Cl)=C3)Cl)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Smo
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.