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Products Details
Product Description
– IHC3 is a competitive and reversible MAO-B inhibitor (IC50: 1.672 μM). IHC3 can interact with the amino acid Cys172 of MAO-B. IHC3 can be used for neurological diseases research[1].
Web ID
– HY-149477
Shipping
– Room temperature
Molecular Formula
– C17H12FN3O
References
– [1]Manoharan A, et al. Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson’s Disease. Molecules. 2023 Aug 21;28(16):6167.
Molecular Weight
– 293.30
SMILES
– FC1=CC=C(NC(/C2=NN=CC=CC3=CC=CC=C3)=O)C2=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Monoamine Oxidase
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
