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IEM-1925 (bromide)
$338 – $540
Products Details
Product Description
– IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy[1][2].
Web ID
– HY-103232
Shipping
– Room temperature
Molecular Formula
– C17H30Br2N2
References
– [1]D B Tikhonov, et al. Voltage-dependent block of native AMPA receptor channels by dicationic compounds. Br J Pharmacol. 2000 Jan;129(2):265-74.|[2]S. I. Vataev, et al. IEM-1925, a Glutamate Receptor Channel Blocker, Increases the Latent Period and Decreases the Duration of Status Epilepticus in Rats in a Lithium-Pilocarpine Model of Epilepsy. Neuroscience and Behavioral Physiology volume 51, pages976–984 (2021).
CAS Number
– 258282-23-4
Molecular Weight
– 422.24
SMILES
– NCCCCCNC1(C2=CC=CC=C2)CCCCC1.Br.Br
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
