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IDX184
$561 – $4,134
Products Details
Product Description
– IDX184 is a potent and orally bioavailable inhibitor of HCV replication. IDX184 potently inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3 nM)[1][2].
Web ID
– HY-19558
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-anti-virus
Molecular Formula
– C25H35N6O9PS
References
– [1]Xiao-Jian Zhou , et al. Safety and Pharmacokinetics of IDX184, a Liver-Targeted Nucleotide Polymerase Inhibitor of Hepatitis C Virus, in Healthy Subjects. Antimicrob Agents Chemother. 2011 Jan;55(1):76-81.|[2]IN VITRO ANTIVIRAL ACTIVITY AND PHARMACOLOGY OF IDX184, A NOVEL AND POTENT INHIBITOR OF HCV REPLICATION.
CAS Number
– 1036915-08-8
Molecular Weight
– 626.62
Compound Purity
– 99.80
SMILES
– C[C@]([C@](O[C@@H]1CO[P](NCC2=CC=CC=C2)(OCCSC(C(C)(C)CO)=O)=O)([H])N3C(NC(N)=NC4=O)=C4N=C3)([C@@H]1O)O
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– HCV;HCV Protease
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
