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Products Details
Product Description
– IDO1/TDO-IN-6 (compound 11) is a dual inhibitor of IDO1/TDO with IC50s of 2.25 and 2.89 μM, respectively. IDO1/TDO-IN-6 has inhibitory effects on IDO1 and TDO, with Ki values of 1.9 and 3.1 μM, respectively. IDO1/TDO-IN-6 can be used in cancer and immunology research[1].
Web ID
– HY-149411
Shipping
– Room temperature
Molecular Formula
– C20H17NO5
References
– [1]Mei-Fen Bao, et al. Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens. Phytochemistry. 2023, 214:113794.
CAS Number
– 2948772-71-0
Molecular Weight
– 351.35
SMILES
– O=C1C2=C(C(OC)=C(OC)C=C2)C(C3=C1N(C)C=CC3=C4)=C(OC)C4=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Indoleamine 2,3-Dioxygenase (IDO)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
