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Products Details
Product Description
– IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC50 of 0.44 μM in hela cells[1].
Web ID
– HY-144468
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H32BrClFN5O2
References
– [1]Yunze Wu, et al. Discovery of novel IDO1 inhibitors targeting the protein’s apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021 Nov 15;52:128373.
CAS Number
– 2677054-58-7
Molecular Weight
– 604.94
SMILES
– O=C(NC1=CC(/C(NO)=NC2=CC=C(C(Br)=C2)F)=CC=C1N(CC(C)C)CC(C)C)NC3=CC=C(C=C3)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Indoleamine 2,3-Dioxygenase (IDO)
Isoform
– IDO1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
