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Products Details
Product Description
– IDO1-IN-15 is a potent IDO1 inhibitor (IC50=127 nM). IDO1-IN-15 has comparable potency against IDO1 enzyme in vitro with Epacadostat[1].
Web ID
– HY-144465
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H14BrFN6O3
References
– [1]Wu Y, et al. Discovery of novel IDO1 inhibitors targeting the protein’s apo form through scaffold hopping from holo-IDO1 inhibitor. Bioorg Med Chem Lett. 2021;52:128373.
CAS Number
– 2126853-17-4
Molecular Weight
– 401.19
SMILES
– CCCNC(NC1=NON=C1/C(NC2=CC=C(C(Br)=C2)F)=N/O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Indoleamine 2,3-Dioxygenase (IDO)
Isoform
– IDO1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
