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IDO/TDO-IN-1
$150 – $4,500
Products Details
Product Description
– IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1].
Web ID
– HY-128355
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H24FN5
References
– [1]Tu W, et al. Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors. ACS Med Chem Lett. 2019 Jun 3;10(6):949-953.
CAS Number
– 2033173-01-0
Molecular Weight
– 413.49
Compound Purity
– 99.22
SMILES
– CN1N=CC(C2=CC=C(N3CCC([C@@H](C4=C5C=CC=C4F)N6C5=CN=C6)CC3)C=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 30 mg/mL (ultrasonic;adjust pH to 2 with HCl)
Target
– Indoleamine 2,3-Dioxygenase (IDO)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
