Products Details

Product Description

– IDO antagonist-1 (compound 163) is an antagonist of IDO . IDO antagonist-1 inhibits pancreatic adenocarcinoma cells growth in C57BL/6 mice[1].

Web ID

– HY-160025

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C39H53N7O5

References

– [1]Timothy F. Briggs, et al. Macrocyclic compounds for the inhibition of indoleamine-2,3-dioxygenase activity and use thereof. WO2018053302A1. 2018-03-22.

CAS Number

– 2206797-88-6

Molecular Weight

– 699.88

SMILES

– O=C([C@H](NC(C1=CC=CC=C1OCC2=CN3N=N2)=O)CC(C)C)N(CCC4)[C@@]4([H])C(N([C@H](C(NCCCCCCCC3)=O)CC5=CC=CC=C5)C)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Indoleamine 2,3-Dioxygenase (IDO)

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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