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IDO antagonist-1
SKU
HY-160025-Get quote
Category Reference compound
Tags 3-Dioxygenase (IDO), Cancer, Indoleamine 2, Metabolic Enzyme/Protease
Products Details
Product Description
– IDO antagonist-1 (compound 163) is an antagonist of IDO . IDO antagonist-1 inhibits pancreatic adenocarcinoma cells growth in C57BL/6 mice[1].
Web ID
– HY-160025
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C39H53N7O5
References
– [1]Timothy F. Briggs, et al. Macrocyclic compounds for the inhibition of indoleamine-2,3-dioxygenase activity and use thereof. WO2018053302A1. 2018-03-22.
CAS Number
– 2206797-88-6
Molecular Weight
– 699.88
SMILES
– O=C([C@H](NC(C1=CC=CC=C1OCC2=CN3N=N2)=O)CC(C)C)N(CCC4)[C@@]4([H])C(N([C@H](C(NCCCCCCCC3)=O)CC5=CC=CC=C5)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Indoleamine 2,3-Dioxygenase (IDO)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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