Download Files:
IDH1 Inhibitor 7-d2
$780 – $3,150
Products Details
Product Description
– IDH1 Inhibitor 7-d2 is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC50 of less than 100 nM[1][2].
Web ID
– HY-150238S
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H22D2F3N7O
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Lei Jang, et al. Compound having mutant idh inhibitory activity, preparation method and use thereof. Patent WO2017162133A1.
CAS Number
– 2135309-51-0
Molecular Weight
– 461.48
Compound Purity
– 99.93
SMILES
– O=C1NC([2H])([2H])[C@H](C(C)C)N1C2=NC(N[C@H](C3=CN(C4=CC=C(C(F)(F)F)C=C4)C=N3)C)=NC=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Isocitrate Dehydrogenase (IDH)
Pathway
– Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
