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iCRT3
$80 – $580
Products Details
Product Description
– iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription.
Web ID
– HY-103705
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H26N2O2S
References
– [1]Xiao H, et al. A Novel Positive Feedback Loop Between NTSR1 and Wnt/β-Catenin Contributes to Tumor Growth of Glioblastoma. Cell Physiol Biochem. 2017 Oct 24;43(5):2133-2142.|[2]Chatterjee SS, et al. Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. J Cell Biol. 2015 Oct 12;211(1):39-51.|[3]Sharma A, et al. Mitigation of sepsis-induced inflammatory responses and organ injury through targeting Wnt/β-catenin signaling. doi: 10.1038/s41598-017-08711-6.
CAS Number
– 901751-47-1
Molecular Weight
– 394.53
Compound Purity
– 99.42
SMILES
– O=C(NCCC1=CC=CC=C1)CSCC2=C(C)OC(C3=CC=C(CC)C=C3)=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 150 mg/mL (ultrasonic;warming)
Target
– Apoptosis;Wnt
Pathway
– Apoptosis;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
