Download Files:
Products Details
Product Description
– ICMT-IN-21 (compound 6ag) is an ICMT inhibitor (IC50=8.8 μM), a sulfonamide-modified farnesyl cysteine (SMFC). The farnesyl and carboxylic acid motifs of ICMT-IN-21 are important structures for inhibiting ICMT[1].
Web ID
– HY-149707
Shipping
– Room temperature
Molecular Formula
– C22H33NO4S3
References
– [1]Majmudar JD, et al. Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors. Bioorg Med Chem Lett. 2011 May 1;21(9):2616-20.
CAS Number
– 1310740-69-2
Molecular Weight
– 471.70
SMILES
– O=S(C1=CC=CS1)(N[C@H](C(O)=O)CSC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– ICMT
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
