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ICI 89406
SKU
HY-15726-1mg
Category Reference compound
Tags Adrenergic Receptor, GPCR/G Protein;Neuronal Signaling, Metabolic Disease
$150
Only 1000 item(s) left in stock.
Products Details
Product Description
– ICI 89406 is a selective β1 adrenergic receptor antagonist amenable to labelling with positron emitters, for PET[1][2].
Web ID
– HY-15726
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C19H22N4O3
References
– [1]Marilyn P Law, et al. Are [O-methyl-11C]derivatives of ICI 89,406 beta1-adrenoceptor selective radioligands suitable for PET? Eur J Nucl Med Mol Imaging. 2008 Jan;35(1):174-85.|[2]B Costall, et al. Changes in dopamine receptor status after denervation or chronic receptor stimulation [proceedings]. Br J Pharmacol. 1979 Jul;66(3):492P-493P.
CAS Number
– 53671-71-9
Molecular Weight
– 354.40
SMILES
– O=C(NC1=CC=CC=C1)NCCNCC(O)COC2=CC=CC=C2C#N
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– β adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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