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Products Details
Product Description
– Ibodutant (MEN 15596) is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1.
Web ID
– HY-14770
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C37H48N4O4S
References
– [1]Cialdai C, et al. MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist. Eur J Pharmacol. 2006 Nov 7;549(1-3):140-8.
CAS Number
– 522664-63-7
Molecular Weight
– 644.87
SMILES
– CC1=CC2=C(C=C(C(NC3(CCCC3)C(N[C@@]([H])(C(NCC4CCN(CC5CCOCC5)CC4)=O)CC6=CC=CC=C6)=O)=O)S2)C=C1
Clinical Information
– Phase 3
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Neurokinin Receptor
Isoform
– NK2
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
