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Iberin
$50 – $180
Products Details
Product Description
– Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC50 of 2.3 μM in HL60 cell. Iberin induces apoptosis.
Web ID
– HY-101413
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C5H9NOS2
References
– [1]Jakubikova J, et al. Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Res. 2005 Sep-Oct;25(5):3375-86.|[2]Jadhav U, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells.|[3]Jadhav U, et al. Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells. J Pharmacol Sci. 2007 Feb;103(2):247-51.|[4]Jakobsen TH, et al. Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorumsensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-21.|[5]Munday R, et al. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71.
CAS Number
– 505-44-2
Molecular Weight
– 163.26
Compound Purity
– 98.0
SMILES
– O=S(CCCN=C=S)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|Ethanol : 10 mg/mL (ultrasonic)
Target
– Apoptosis;Bacterial;Endogenous Metabolite
Pathway
– Anti-infection;Apoptosis;Metabolic Enzyme/Protease
Product type
– Natural Products
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