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Products Details
Product Description
– IACS-9439 is a potent, selective, and orally active CSF1R inhibitor with a Ki value of 1 nM inhibitor. IACS-9439 can be used for advanced solid tumors research[1].
Web ID
– HY-153243
Shipping
– Room temperature
Molecular Formula
– C23H27N7O3S
References
– [1]Barbara Czako, et al. Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R. J Med Chem. 2020 Sep 10;63(17):9888-9911.
CAS Number
– 2231259-36-0
Molecular Weight
– 481.57
SMILES
– COC1=C2C(SC(N[C@@H]3[C@H](CCCC3)O)=N2)=CC(OCC4=NC(NC5=CN(N=C5)C)=NC=C4)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Fms
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
