Download Files:
Products Details
Product Description
– IACS-52825 is a potent and selective DLK inhibitor with Kd of 1.3 nM, useful for the study of chemotherapy-induced peripheral neuropathy[1].
Web ID
– HY-155089
Shipping
– Room temperature
Molecular Formula
– C16H13F7N4O2
References
– [1]Kang Le, et al. Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy. J Med Chem. 2023 Jul 27;66(14):9954-9971.
CAS Number
– 2640376-72-1
Molecular Weight
– 426.29
SMILES
– NC1=NC=C(C=C1OC(F)(F)F)C2=CN(C([C@@H](O)C(F)(F)F)=N2)C34CC(C3)(C4)F
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– MAP3K
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
