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IA-Alkyne
SKU
HY-136205-10 mg
Category Reference compound
Tags Infection; Inflammation/Immunology, Membrane Transporter/Ion Channel;Neuronal Signaling, TRP Channel
$160 – $980
Products Details
Product Description
– IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection[1]. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling[2]. IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-136205
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C8H12INO
References
– [1]David L. Use of trp channel agonists to treat infections. Patent US20130203715A1.|[2]Zorin NA, et al. Inhibition by iodoacetamide and acetylene of the H-D-exchange reaction catalyzed by Thiocapsa roseopersicina hydrogenase. Eur J Biochem. 1996 Oct 15;241(2):675-81.
CAS Number
– 930800-38-7
Molecular Weight
– 265.09
Compound Purity
– 99.90
SMILES
– O=C(NCCCCC#C)CI
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.