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Hydralazine (hydrochloride)
$60 – $180
Products Details
Product Description
– Hydralazine hydrochloride is a orally active antihypertensive agent, reduces peripheral resistance directly by relaxing the smooth muscle cell layer in arterial vessel. Hydralazine hydrochloride has antioxidant activity, as well as inhibits ROS release and O2·- generation with an IC50 value of 9.53 mM and 1.19 mM, respectively[1][2].
Web ID
– HY-B0464
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C8H9ClN4
Citations
– Neurosci Bull. 2020 Oct;36(10):1158-1170.|J Pharm Anal. 2023 Aug 11.
References
– [1]Bourreli, B., et al., Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion. Can J Anaesth, 1988. 35(3 ( Pt 1)): p. 242-8.|[2]Kandler, M.R., et al., Hydralazine for essential hypertension. Cochrane Database Syst Rev, 2010(8): p. CD004934.
CAS Number
– 304-20-1
Molecular Weight
– 196.64
Compound Purity
– 99.66
SMILES
– NNC1=NN=CC2=C1C=CC=C2.Cl
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic;adjust pH to 11 with NaOH)|H2O : 25 mg/mL (ultrasonic)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
