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hVEGF-IN-2
$316
Only 1000 item(s) left in stock.
Products Details
Product Description
– hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents[1].
Web ID
– HY-148316
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H18N2O2
References
– [1]Sun L, et al. Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases. J Med Chem. 1998 Jul 2;41(14):2588-603.
CAS Number
– 186610-88-8
Molecular Weight
– 306.36
SMILES
– O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(N4CCOCC4)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– VEGFR
Isoform
– VEGFR1/Flt-1
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
