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Products Details
Product Description
– Huanglongmycin N is a DNA topoisomerase I inhibitor (EC50 = 14 μM).
Web ID
– HY-N10115
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H16O5
References
– [1]Zhu S, et al. Discovery of a DNA Topoisomerase I Inhibitor Huanglongmycin N and Its Congeners from Streptomyces sp. CB09001. J Org Chem. 2021 Dec 3;86(23):16675-16683.
CAS Number
– 2881024-09-3
Molecular Weight
– 324.33
SMILES
– OC1=C(CC)C=CC(C2=O)=C1C(C3=C2C=C(C)C(C(C)=O)=C3O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Topoisomerase
Isoform
– Topo I
Pathway
– Cell Cycle/DNA Damage
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
