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Products Details
Product Description
– HTMT (dimaleate) is a potent histamine H1 and H2 receptor agonist. HTMT (dimaleate) is 4 x 104 times more active than histamine in H2-mediated effects in natural suppressor cells[1].
Web ID
– HY-101052
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H33F3N4O9
References
– [1]Khan MM, Marr-Leisy D, Verlander MS, Bristow MR, Strober S, Goodman M, Melmon KL. The effects of derivatives of histamine on natural suppressor cells. J Immunol. 1986 Jul 1;137(1):308-14.
CAS Number
– 195867-54-0
Molecular Weight
– 614.57
SMILES
– CC(NCCC1=CN=CN1)CCCCC(NC2=CC=C(C(F)(F)F)C=C2)=O.O=C(O)/C=CC(O)=O.O=C(O)/C=CC(O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Isoform
– H1 Receptor;H2 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
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