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Products Details
Product Description
– HSR1304 (Compound 5d) is a potent inhibitor of NFκB. The multifunctional transcription factor, nuclear factor-κB (NF-κB), is broadly involved in multiple human diseases, such as cancer and chronic inflammation. HSR1304 has the potential for the research of cancer diseases[1].
Web ID
– HY-144745
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H21ClN2O3
References
– [1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.
CAS Number
– 2763363-08-0
Molecular Weight
– 420.89
SMILES
– COC1=CC=CC=C1NC(C2C3=CC=CC=C3CCN2C(C4=CC=C(C=C4)Cl)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– NF-κB
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
