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Products Details
Product Description
– HSP90-IN-23 (Comp 12-1) is an inhibitor of heat shock protein 90(HSP90) with an IC50 of 9 nM. HSP90-IN-23 induces apoptosis of tumor cells and arrests the tumor cell cycle in G0/G1 phase. HSP90-IN-23 can be used for cancer research[1].
Web ID
– HY-149891
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H24N2O6S
References
– [1]Fang X, et.al. Development of VER-50589 analogs as novel Hsp90 inhibitors. Bioorg Med Chem Lett. 2023 Jul 15;91:129375.
Molecular Weight
– 444.50
SMILES
– OC1=CC(O)=C(C=C1C(C)C)C2=C(C(C(NCC)=O)=NO2)C3=CC=C(C=C3)S(=O)(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HSP
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
