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Products Details
Product Description
– HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively.
Web ID
– HY-153588
Shipping
– Room temperature
Molecular Formula
– C25H30N4O3
References
– [1]Jiang F, et al. Identification and optimization of novel 6-acylamino-2-aminoquinolines as potent Hsp90 C-terminal inhibitors. Eur J Med Chem. 2017 Dec 1;141:1-14.
CAS Number
– 442898-75-1
Molecular Weight
– 434.53
SMILES
– O=C(C1=CC=C(C(OC)=C1)OC)NC2=CC3=C(N=C(N4CCN(CC4)CC)C=C3C)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HSP
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
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